Genomics 101: An Introduction to Next-Generation Sequencing – PediaCast CME 075
- Dr Rick Wilson and Dr Elaine Mardis visit the studio as we consider the basics of genomic medicine. Learn how DNA is sequenced, explored and used to inform the diagnosis, prognosis and management of human disease. We hope you can join us!
Instructions to obtain CME/CE Credit
- Read this information page.
- Listen to the podcast.
- Complete the post test at Nationwide Children’s CloudCME.
- You can view your transcript and print a certificate of completion at Cloud CME.
- Need help creating a Cloud CME account? Click Here.
- Still have questions? Contact CMEOffice@nationwidechildrens.org
- Genomic Medicine
- Next-Generation Sequencing
At the end of this activity, participants should be able to:
- Define these terms: genetics, genome, genomics, transcription, translation, sequencing, assembly and alignment
- Appreciate the significance of genomic variation across the human population.
- Recognize types of genomic alterations, including single nucleotide variants, insertions, deletions and duplications.
- Identify genomic medicine as an opportunity to improve patient care by identifying variations in DNA that inform diagnosis, prognosis and management of human disease.
- Institute for Genomic Medicine at Nationwide Children’s Hospital
- Genome Aggregation Database (gnomAD)
- The Cancer Genome Atlas (TCGA) Program
- Pediatric Cancer Genome Project (PeCan Database)
- Treehouse Childhood Cancer Initiative
- UCSC Genome Browser BLAT Tool
- Integrative Genomics Viewer
- The Sound of Silence: The Impact of “Silent” Genetic Variation in Health and Disease
- Molecular Toolset: Real-Time Screening for SARS-CoV-2 Variants
- Additional Ventures: Investing in Congenital Heart Disease Research to Advance Care
- The Impact of Genomic Medicine: Carter’s Story
- Targeting DIPG: The Most Puzzling of Pediatric Brain Tumors
- Novel Genetic Driver Discovered for Pediatric Meningiomas Using Molecular Profiling
- Cerebral Organoids Provide Insight into Human Brain Development and Neurological Disease Intractable Epilepsy Linked to Brain-Specific Genetic Mutation
- What Can We Learn From the Co-Occurrence of a Genetic Disorder and Cancer?
- New Model Provides Novel View of Congenital Heart Disease
- The Impact of Genomic Medicine: Charlie’s Story
- Genomics Modules on Nationwide Children’s Learning Center
- No one in a position to control content has any relationships with commercial interests.
- Nationwide Children’s has not received any commercial support for this activity.
- In support of improving patient care, Nationwide Children’s Hospital is jointly accredited by the American Nurses Credentialing Center (ANCC), the Accreditation Council for Pharmacy Education (ACPE), and the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for the healthcare team. (1.0 ANCC contact hours; 1.0 ACPE hours; 1.0 CME hours)
- Nationwide Children's Hospital has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credits. Approval is valid for 2 years from the date of the activity. PAs should only claim credit commensurate with the extent of their participation.
- As a Jointly Accredited Organization, Nationwide Children's Hospital is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. State and provincial regulatory boards have the final authority to determine whether an individual course may be accepted for continuing education credit. Nationwide Children's Hospital maintains responsibility for this course. Social workers completing this course receive 1.0 continuing education credits.
- Continuing Education (CE) credits for psychologists are provided through the co-sponsorship of the American Psychological Association (APA) Office of Continuing Education in Psychology (CEP). The APA CEP Office maintains responsibility for the content of the programs.